Publications
Publications since 01.01.2017 (project start):
- T. Fröhlich, A. Kiss, J. Wolfling, E. Mernyak, Á. E. Kulmány, R. Minorics, I. Zupkó, M. Leidenberger, O. Friedrich, B. Kappes, F. Hahn, M. Marschall, G. Schneider, S. B. Tsogoeva. Synthesis of artemisinin-estrogen hybrids highly active against HCMV, P. falciparum, cervical and breast cancer. ACS Med. Chem. Lett., 2018, DOI: 10.1021/acsmedchemlett.8b00381
- J. Toms, V. Reshetnikov, S. Maschauer, A. Mokhir, O. Prante.* Radiosynthesis of an 18F-fluoroglycosylated aminoferrocene for in-vivo imaging of reactive oxygen species activity by PET. J. Labelled Compounds & Radiopharmaceuticals, 2018, accepted on 01.10.2018; DOI:10.1002/jlcr.3687.
- V. Reshetnikov, S. Daum, C. Janko, W. Karawacka, R. Tietze, C. Alexiou, S. Paryzhak, T. Dumych, R. Bilyy, P. Tripal, B. Schmid, R. Palmisano, A. Mokhir.* ROS-responsive N-alkylaminoferrocenes for cancer cell specific targeting of mitochondria. Angew. Chem. Int. Ed., 2018, 57, 11943-11946. Link: https://doi.org/10.1002/anie.201805955
- V. Reshetnikov, J. Hahn, C. Maueröder, C. Czegley, L. E. Munoz, M. Herrmann, M. H. Hoffmann,* A. Mokhir.* Chemical tools for targeted amplification of reactive oxygen species in neutrophils. Frontiers in Immunology, 2018, Aug. 13: 9, 1827; doi: 10.3389/fimmu.2018.01827.
- V. Reshetnikov, A. Arkhypov, P. R. Julakanti, A. Mokhir.* A cancer specific oxaliplatin-releasing Pt(IV)-prodrug. Dalton Trans., 2018, 47, 6679-6682.
- S. Daum, S. Babiy, H. Konovalova, W. Hofer, A. Shtemenko, N. Shtemenko, C. Janko, C. Alexiou, A. Mokhir, A.* Tuning the structure of aminoferrocene-based anticancer prodrugs to prevent their aggregation in aqueous solution. J. Inorg. Biochem., 2018, 178, 9-17.
- C. Fröhlich, C. Reiter, M. E. M. Saeed, C. Hutterer, F. Hahn, M. Leidenberger, O. Friedrich, B. Kappes, M. Marschall, T. Efferth, S. B. Tsogoeva. Synthesis of Thymoquinone–Artemisinin Hybrids: New Potent Antileukemia, Antiviral, and Antimalarial Agents. ACS Med. Chem. Lett., 2018, 9, 534-539.
- T. Fröhlich, F. Hahn, L. Belmudes, M. Leidenberger, O. Friedrich, B. Kappes, Y. Couté, M. Marschall,* S. B. Tsogoeva.* Synthesis of artemisinin-derived di/tri-mers and dendrimers, investigation of their activity against P. falciparum and cytomegalovirus, and insights into their mechanisms of action. Chem. Eur. J., 2018, 24, 8103-8113.
- A. Çapcı Karagöz, C. Reiter, E.-J. Seo, L. Gruber, F. Hahn, M. Leidenberger, V. Klein, F. Hampel, O. Friedrich, M. Marschall, B. Kappes, T. Efferth, S. B. Tsogoeva.* Access to new highly potent antileukemia, antiviral and antimalarial agents via hybridization of natural products (homo)egonol, thymoquinone and artemisinin. Bioorg. Med. Chem. 2018, 26, 3610-3618.
- T. Fröhlich, C. Reiter, M. M. Ibrahim, J. Beutel, C. Hutterer, I. Zeitträger, H. Bahsi, M. Leidenberger, O. Friedrich, B. Kappes, T. Efferth, M. Marschall, S. B. Tsogoeva. Synthesis of Novel Hybrids of Quinazoline and Artemisinin with High Activities against Plasmodium falciparum, Human Cytomegalovirus, and Leukemia Cells. ACS Omega, 2017, 2, 2422-2431.
- F. E. Held, A. A. Guryev, T. Fröhlich, F. Hampel, A. Kahnt, C. Hutterer, M. Steingruber, H. Bahsi, C. von Bojnicic-Kninski, D. S. Mattes, T. C. Foertsch, A. Nesterov-Mueller, M. Marschall, S. B. Tsogoeva, Facile access to potent antiviral quinazoline heterocycles with fluorescence properties via merging metal-free domino reactions. Nature Communications, 2017, 15071.
- C. M. Bock, G. Parameshwarappa, S. Bönisch, W. Bauer, C. Hutterer, M. Leidenberger, O. Friedrich, M. Marschall, B. Kappes, A. Görling, S. B. Tsogoeva. Deeper Insight into the Six-Step Domino Reaction of Aldehydes with Malononitrile and Evaluation of Antiviral and Antimalarial Activities of the Obtained Bicyclic Products. ChemistryOpen, 2017, DOI: 10.1002/open.201700005.