25.04.2024: Prof. Dr. Nicolas Plumeré, Technische Universität München, “Protecting Hydrogenases”
Hörsaal C1, 17:15 Uhr
20.06.2024: Prof. Dr. Paolo Melchiorre, Universita di Bologna, tba
Hörsaal C1, 17:15 Uhr
27.06.2024: Prof. Dr. Annette Beck-Sickinger, Universität Leipzig, ”G Protein-Coupled Peptide Receptors: State of the Art and Innovative Therapeutic Concepts”
Hörsaal C1, 17:15 Uhr
04.07.2024: Prof. Dr. Stefanie Dehnen, Karlsruhe Institute of Technology, “Multinary Cluster Compounds: From Molecular Aesthetics to Macroscopic Functionality”
Hörsaal C1, 17:15 Uhr
Frühere Vorträge
26.10.2023: Dr. Felix Richter, Justus-Liebig Universität Gießen, „Solid-state batteries with polymers as mediators between inorganic materials“
Hörsaal C1, 17:15 Uhr
09.11.2023: Prof. Dr. Birgit Esser, Universität Ulm, „Organic Functional Materials: From Batteries to Conjugated Nanohoops“
Hörsaal C1, 16:15 Uhr
23.11.2023: Prof. Dr. Müge Kasanmascheff, TU Dortmund, „Tracing essential radicals using in vitro and in vivo EPR spectroscopy“
Hörsaal C1, 17:15 Uhr
07.12.2023: Prof. Colin Nuckolls, Columbia University, „Contorted aromatics for energy conversion and storage“
Hörsaal C1, 17:15 Uhr
11.01.2024: Prof. Dr. Thomas Magauer, Universität Innsbruck, „Natural Product Synthesis: Odysseys and Success Stories“
Hörsaal C1, 17:15 Uhr
25.01.2024: Dr. Felix Gnerlich, Astra Zeneca, „New Synthetic Modalities in Drug Discovery – Spotlight on Therapeutic Oligonucleotides and Peptides“
Hörsaal C1, 17:15 Uhr
27.04.2023: Prof. Warren E. Piers, University of Calgary, „Molybdenum Complexes for Ammonia Activation: Mechanisms of Hydrogen Production and N-N Bond Formation“
Hörsaal C1, 17:15 Uhr
11.05.2023: Prof. Christof Sparr, Universität Basel, „Catalyst Control over Higher-Order Stereogenicity“
Hörsaal C1, 17:15 Uhr
25.05.2023: Prof. Peter H. Seeberger, Max-Planck-Institut für Kolloid- und Grenzflächenforschung, „Carbohydrate-Based Material Science and Medicines Produced in Flow“
Hörsaal C1, 17:15 Uhr
22.06.2023: Prof. Anna Hirsch, Helmholtz-Institut für Pharmazeutische Forschung Saarland, „Target-based anti-infective drug discovery“
Hörsaal C1, 15:15 Uhr
20.07.2023: Prof. Thorsten Stumpf, Helmholtz-Zentrum Dresden-Rossendorf, „Nukleares Endlager: Grundlagenforschung zum Standortauswahlprozess?“
Hörsaal C1, 17:15 Uhr
03.11.2022: Dr. Dana Medina-Tautz, LMU München, „Let’s Put it on the Surface – Thin Films of Crystalline and Porous Frameworks“
Hörsaal C1, 17:15 Uhr
17.11.2022: Prof. Mogens Brøndsted Nielsen, University of Copenhagen, „Extended Tetrathiafulvalenes with Carbon-rich Cores“
Hörsaal C1, 17:15 Uhr
01.12.2022: Prof. Abner de Siervo, Universität Campinas / Brasilien, „Bottom-up synthesis of new 2D materials: from nanoporous graphene to epitaxial TMDs“
Hörsaal C1, 17:15 Uhr
15.12.2022: Prof. Sebastian Habig, FAU, LS für Didaktik der Chemie, „Moderne Medien zur Vermittlung chemischer Inhalte – Alter Wein in neuen Schläuchen?“
Hörsaal C1, 17:15 Uhr
12.01.2023: Prof. Andreas Kirschning, Leibniz Universität Hannover, „Chemische Terpensynthese verbunden mit Terpencyclasen als Synthese-Tools“
Hörsaal C1, 17:15 Uhr
26.01.2023: Prof. Ingrid Hilger, Friedrich-Schiller-Universität Jena, „Nanotheranostische Ansätze zur Adressierung von entzündungsassoziierten Erkrankungen“
Hörsaal C1, 17:15 Uhr
02.02.2023: Dr. Carolin Müller, Universität Luxemburg, „Molecules in the Excited-State – A tale of practice and theory“
Hörsaal C1, 17:15 Uhr
09.02.2023: Prof. Martin Albrecht, Universität Bern, „Tailoring ligands for challenging oxidation catalysis“
Hörsaal C1, 17:15 Uhr
23.02.2023: Prof. Anna Fischer, Albert-Ludwigs-Universität Freiburg, „Design of Nanostructured Materials for Electrochemical Energy Systems“
Hörsaal C1, 17:15 Uhr
19.05.2022: Prof. Frank Neese, Max-Planck-Institut Mühlheim an der Ruhr, „Insight into the nature of high valent iron centers as reaction intermediates in biological and homogeneous catalysis from a combination of spectroscopy and quantum chemistry“
Hörsaal C1, 17:15 Uhr
09.06.2022: Prof. Bill Morandi, ETH Zürich, „Recent Development in Shuttle Catalysis“
Hörsaal C1, 17:15 Uhr
30.06.2022: Prof. Franc Meyer, Georg-August-Universität Göttingen, „Bioinspired Small Molecule Activation for Energy-Related Catalysis“
Hörsaal C1, 17:15 Uhr
14.07.2022: Prof. Tobias Kraus, Universität des Saarlandes, „Connecting material properties to molecular structure with hierarchical networks“
Hörsaal C1, 17:15 Uhr
21.07.2022: Prof. Jean-Hubert Olivier, University of Miami, „Expanding the Toolbox to Modulate the Electronic Functions of Light-Harvesting Nanomaterials and Functionalized Electrodes“
Hörsaal C1, 17:15 Uhr
28.07.2022: Prof. Qing Ye, Julius-Maximilians-Universität Würzburg, „Three-Dimensional Analogues of Boron-containing Tused Polycyclic π Systems“
Hörsaal C1, 17:15 Uhr
18.11.2021: Prof. Dr. Thomas Strassner, TU Dresden, „Blue Phosphorescent OLED Emitters“
Hörsaal C1, 17:15 Uhr
02.12.2021: Prof. Dr. Eva Hevia, Universität Bern, „Bespoke Bimetallics for Chemical Cooperativity“
Hörsaal C1, 17:15 Uhr
16.12.2021: Prof. Dr. Maik Eichelbaum, TH Nürnberg, „Forschung für die Energiewende“
Hörsaal C1, 17:15 Uhr
20.01.2022: Prof. Dr. Karl-Heinz Jacob, TH Nürnberg, „Tieftemperaturverhalten von Schmierfetten und Schmierölen“
Hörsaal C1, 17:15 Uhr
03.02.2022: Prof. Dr. Anna Fischer, Albert-Ludwigs-Universität Freiburg,
Hörsaal C1, 17:15 Uhr
17.02.2022: Prof. Dr. David Scheschkewitz, Universität des Saarlandes, „Training instead of Taming: Functionalisation of Reactive Unsaturated Group 14 Species“
Hörsaal C1, 17:15 Uhr
12.11.2020: Prof. Dr. Guido Clever, Technische Universität Dortmund, „Heteroleptic Coordination Cages: Assembly, Functionalization and Fullerene Binding“
24.10.2019: Prof. Dr. Jan Weigand, Technische Universität Dresden, „The Chemistry of P4 – A Problem for the Environment?“
30.10.2019: Prof. Dr. Luis M. Liz-Marzán, BioNanoPlasmonicsLaboratory, CIC biomaGUNE San Sebastián, „Chemical Design of Nanoplasmonic Sensors“, !!! Die Veranstaltung findet am Mittwoch um 10:00 im C1 (Chemikum) statt !!!
07.11.2019: Prof. Dr. Mathias Christmann, Freie Universität Berlin, „Step-Effi cient Syntheses of Polycyclic Terpenes“
21.11.2019: Prof. Dr. Thomas Klapötke, LMU München „TKX-50: A new high explosive developed at LMU“
05.12.2019: Prof. Dr. Ingo Ott, Technische Universität Braunschweig „On the Medicinal Chemistry of Gold Organometallics”
16.01.2020: Prof. Dr. Herbert Mayr, Ludwig-Maximilians-Universität München „Philicities, Fugalities and Equilibrium Constants: A Quantitative Approach to Polar Organic Reactivity”
30.01.2020: Prof. Dr. Antonio Mezzetti, ETH Zürich „Base Metal Catalysts with Macrocyclic N2P2 Ligands for Ketone Hydrogenation and Beyond“
25.04.2019: Prof. Dr. Todd B. Marder, Universität Würzburg, „Transition Metal Catalyzed Borylation of C-H and C-X Bonds: Synthesis of Aryl and Alkyl Boronates With and Without
Photons“
09.05.2019: Prof. Dr. Andreas Koehn, Universität Stuttgart, „Is Chemistry computable?“
23.05.2019: Prof. Dr. Hans-Guenther Schmalz, Universität zu Köln, „Biology-driven Synthesis of natural products and designed non-natural bioactive molecules“
13.06.2019 (!!! ab 16:15 !!! 2 Vorträge !!!):
Prof. Dr. Carsten Krebs, Pennsylvania State University „Different strategies for metalloenzymatic functionalization of unactivated C-H bonds” und
Prof. Val Vullev, University of California, Riverside, „Dynamics in a Broad Scale: Biological Inspiration for Charge Transfer and Interfaces”
04.07.2019: Prof. Dr. Thomas Müller, Universität Düsseldorf, „Diversity Oriented Synthesis of Functional Dyes via Palladium and Copper Catalysis”
15.10.2018: Campus Event (die Veranstaltung findet im Hörsaal C3 statt); Link: https://www.chemie.nat.fau.de/2018/09/21/gdch-campus-event-kommt-nach-erlangen/
18.10.2018: Prof. Dr. Lutz F. Tietze, Institut für Organische und Biomolekulare Chemie, Universität Göttingen, Thema „Domino Reactions. The Green and Economical Art of Chemical Synthesis„.
08.11.2018: Prof. Zoltan Konya (George-de-Hevesy-Namensvorlesung), Department of Applied and Environmental Chemistry, University of Szeged, Thema „Beyond the nanoparticles: the role of sub-nanosized metal species in heterogeneous catalysis„
22.11.2018: Dr. Guenter Schmid, Siemens AG, Thema „Technical Photosynthesis Employing Single Step Direct Electrocatalytic Reduction of CO2 Toward CO and Hydrocarbons„
06.12.2018: Prof. Christian Limberg, Humboldt-Universität zu Berlin, Thema „Understanding of functional entities in solid catalysts and enzymes with the aid of molecular mimics – mini-zeolites and COx conversion„
10.01.2019: Prof. Dr. Stefanie Dehnen, Philipps-Universität Marburg, Thema „Multinary Clusters – Between Exotic Structures and Potential Use„
24.01.2019: Prof. Michal Hocek, the laboratory of Bioorganic Medicinal Chemistry of Nuelcic Acid, Academy of Sciences of Czech Republik, Thema „Base-modified nucleosides and nucleotides as cytostatics or building blocks for enzymatic synthesis of modified nucleic acids„.
07.02.2019: Prof. Dr. Lutz Ackermann, the laboratory of Catalysts and Organic Synthesis, Universität Göttingen, Thema „Selectivity Control in Catalyzed C-H Activation„.
12.04.2018: Prof. Dr. Christoph Lambert, Universität Würzburg, Thema „Can magnetic fields influence chemical reactions? About charlatans and electron spins„Abstract: Magnetic fields interact with matter in various ways and are often believed to be either dangerous to human beings or may heal several illnesses. But can magnetic fields really influence physiological processes, that is, chemical reactions? This talk will give insight into the mechanisms of magnetic field effects (MFE) in chemistry and present examples how the MFE act in charge separated radical pairs. These spin-correlated radical pairs are formed by photoinduced electron transfer processes in molecular triads consisting of an electron donor, a transition metal complex photosensitizer, and an electron acceptor
26.04.2018: Prof. Oliver Seitz, Humboldt-Universität zu Berlin, Thema „Imaging and Hijacking of RNA„Abstract: A current challenge in the field is the imaging and quantification of specific RNA molecules in live cells. We have introduced the FIT-Probes, i.e. quencher-free hybridization probes which contain a single asymmetric cyanine dye that serves as a fluorescent base surrogate.[1] The ‘dye base’ acts as a local intercalator probe and reports hybridization. The combination with additional dyes and/or the introduction of a local constraint in the vicinity of the ‘dye base’ enables designs which provide exceptional brightness and quantitative imaging of RNA.[2] I will show that Enhanced FIT-Probes enable the imaging of the dynamics of small, oskar mRNA containing ribonucleotide particles in developing Drosophila melanogaster oocytes and of small viral RNA upon Influenza infection.[3] Recently, we extended the color repertoire of DNA FIT probes.[4] I will discuss the prospects for imaging of single nucleotide alterations introduced in cells upon mRNA C→U editing.DNA and RNA are informational molecules. I will show how the information encoded in DNA/RNA can be hijacked. We consider nucleic acid molecules as templates that provide unique opportunities for the controlled presentation of functional units.[5] For example, the controlled presentation of peptides on antisense compounds provides opportunities for enhancing cytotoxicity by perturbation of select protein-protein interactions.[6] Nucleic acids can be used as templates that trigger chemical reactions. We explore whether RNA templated reactions[7] can be used for the design of molecular doctors, which initiate the synthesis of drug-like compounds only in those cells expressing particular RNA sequences.[1] F. Hövelmann, O. Seitz, Acc. Chem. Res. 2016, 49, 714; [2] I. Gaspar, F. Hövelmann, J. Chamiolo, A. Ephrussi, O. Seitz, ACS Chem. Biol.2018, 13, 742; [3] a) F. Hövelmann, I. Gaspar, S. Loibl, E.A. Ermilov, B. Röder, A. Ephrussi, O. Seitz, Angew. Chem. Int. Ed. 2014, 53, 11370; b) I. Haralampiev, M. Schade, J. Chamiolo, F. Jolmes, S. Prisner, P.T. Witkowski, M. Behrent, F. Hövelmann, T. Wolff, O. Seitz, A. Herrmann, ChemBioChem2017, 18, 1589; [4] F. Hövelmann, I. Gaspar, J. Chamiolo, M. Kasper, J. Steffen, A. Ephrussi, O. Seitz, Chem.Sci 2016, 7, 128; [5] V. Bandlow, S. Liese, D. Lauster, K. Ludwig, R.R. Netz, A. Herrmann, O. Seitz, J. Am. Chem. Soc.2017, 139, 16389; [6] F. Abendroth, O. Seitz, Angew. Chem. Int. Ed.2014, 53, 10504; [7] M. Di Pisa, A. Hauser, O. Seitz, ChemBioChem2017, 18, 872.
17.05.2018: PD Dr. Felix Zelder, University of Zürich, Thema „Chemistry, Biomimetic Studies and Applications with Vitamin B12 Derivatives and Related Macrocycles„Abstract: Cobalamins (Cbls) play important roles as enzymatic cofactors, photoreceptors and allosteric effectors in biological systems. In Cbl-protein and Cbl-nucleic acid complexes, biological function is often controlled by unique structural features of the organometallic cobalt-containing corrin macrocycles.[1] My group develops modified B12 derivatives and related macrocycles for fundamental studies, analytical purposes and potential medicinal applications.[2] Recently, we developed an immobilisation strategy for mimicking an important proton relay mechanism in cofactor-B12 protein complexes.[3] In other studies, we focus on developing B12 derivatives as inhibitors of bacterial and cancer cells growth.[2] In our analytical chemistry program, we develop metal-complexes for detecting small molecules and ions in competitive biological media.[4][1] J. Bridwell-Raab, C. L. Drennan, Curr. Opin. Chem. Biol. 2017, 37, 63-70; [2] F. Zelder, Chem. Commun. 2015, 51, 14004-14017; [3] M. Sonnay, T. Fox, O. Blacque, F. Zelder, Chem. Sci. 2016, 7, 3836-3842; [4] N. Kumari, F. Zelder, Chem. Commun. 2015, 51, 17170-17173.
07.06.2018: Prof. Beate Koksch, Freie Universität Berlin, Thema „Fluorine in Peptide and Protein Engineering„Abstract: In a league of its own, fluorine has the potential to enable us to engineer biopolymers with highly desirable properties. However, the particular challenge in using it as a tool lies in our ability to juggle the interplay between the specific properties of the fluorinated building block and its responsiveness to the environment it is exposed to.Fluorine has been shown to impart often favorable but seldom predictable properties to peptides and proteins, a phenomenon that is caused by the nature of the fluorine atom and properties of the C-F bond. Up until about two decades ago, the outcomes of fluorine modification of peptides and proteins were largely left to chance. Driven by the motivation to extend the application of the unique properties of the element fluorine from medicinal and agro chemistry to peptide and protein engineering we have established multiple peptide and protein models with different properties for the purpose of studying the consequences of fluorine substitution in the context of a protein environment.In general, the consequences of incorporating the C-F bond into a biopolymer can be attributed to two distinct yet related phenomena: 1) the fluorine substituent can directly engage in intermolecular interactions with its environment and/or 2) the other functional groups present in the molecule can be influenced by the electron withdrawing nature of this element (intramolecular) and in turn interact differently with their immediate environment (intermolecular). Also, we could show that not only the nature of the side chain but also its immediate environment determine the outcome of this substitution.We have especially been fascinated to observe that the difference of as subtle as one fluorine atom in the side chain of an amino acid can dramatically influence the key properties of peptides and proteins such as hydrophobicity, polarity and secondary structure propensity. These properties are crucial factors in peptide and protein engineering as they direct properties as important as proteolytic stability and folding, and thus affect protein function. One of our current projects studies the way in which not just biomolecules in the laboratory, but whole living organisms accommodate fluorine and this talk will introduce our first results of this endeavor.A.A. Berger, J.-S. Völler, N. Budisa, B. Koksch. Acc. Chem. Res. 2017, 50 (9), 2093-2103; Völler, M. Dulic, U. Gerling-Driessen, H. Biava, T. Baumann, N. Budisa, I. Gruic-Sovuli, B. Koksch. ACS Central Science 2017, 3 (1), 73–80; Ye, B. Loll, A.A. Berger, U. Mülow, C. Alings, M. Wahl, B. Koksch. Chem. Sci. 2015, 6, 5246 – 5254; U.I.M. Gerling, M. Salwiczek, C.D. Cadicamo, H. Erdbrink, S. Grage, P. Wadhwani, A. Ulrich, M. Behrens, G. Haufe, C. Czekelius, B. Koksch. Chem. Sci. 2014, 5 (2), 819-830; Nyakatura, O. Reimann, T. Vagt, M. Salwiczek, B. Koksch. RSC Advances 2013, 3 (18), 6319 – 6322; Salwiczek, E.K. Nyakatura, U.I.M. Gerling, S. Ye, B. Koksch. Chem.Soc.Rev. 2012, 41 (6), 2135 – 2171; Salwiczek, S. Samsonov, T. Vagt, C. Baldauf, E. Nyakatura, E. Fleige, J. Numata, H. Cölfen, M. T. Pisabarro, B. Koksch. Chem. Eur. J. 2009, 15 (31,) 7628-7636; C. Jäckel, M. Salwiczek, B. Koksch. Angew. Chem. Int. Ed., 2006, 45, 4198-4203
21.06.2018: Prof. Roger Alberto, University of Zürich, Thema „TBA“
05.07.2018: Prof. Dr. Stephan A. Sieber, Technische Universität München, Thema „TBA“
26.10.2017: Prof. Dr. Manfred Scheer, Universität Regensburg, „Kohlenstoff und Phosphor – Eine „schräge“ Partnerschaft“
16.11.2017: Prof. Dr. Uhl Werner, Universität Münster, „Aluminium-Phosphor-basierte Frustrierte Lewis-Paare – P-H-Funktionalisierung und Reaktionen mit a,b-ungesättigten Carbonyl-Verbindungen“
07.12.2017: Prof. Dr. Michael Hill, University of Bath, UK, „Nucleophilic boron: the easy way“
21.12.2017: Prof. Dr. Oliver Wenger, University of Basel, „From Photoinduced Electron Transfer to Charge Accumulation and New Photosensitizers“
18.01.2018: Prof. Dr. Angela Casini, Cardiff University, „A golden future in bioinorganic chemistry: the promise of bioactive gold complexes as probes and therapeutic agents“
25.01.2018: Prof. Dr. Nicolas Winssinger, University of Geneva, Switzerland, „PNA-programmed Self Assemblies in Chemical Biology“
